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Potential Sciences获种子轮融资做物理模拟药物发现

AI 总结

据WIRED报道,英国初创公司Potential Sciences于11月5日成立,并获得英国政府AI风投基金SovAI、Twin Path Ventures等投资的数千万美元种子轮融资,确切金额与估值未披露。该公司计划通过模拟从原子到分子、氨基酸和蛋白质的相互作用,构建大规模化学数据集,并据此训练用于识别靶向药物候选的AI模型。创始人兼CEO Hatem Helal表示,目标是让注定临床失败的分子尽快失败,并让个体化定制药物在经济上可行;学者则指出,精确预测蛋白质结合仍需重大突破。

深度见解

SovAI背书使该公司与Basecamp Research、Isomorphic Labs、CuspAI并列于英国政府支持的AI药物发现阵营,而该基金拥有约8亿美元资金并可对接国家AI超算;WIRED同时提醒其蛋白质结合预测能力尚未验证,且更快筛选候选分子并不能替代安全性与有效性测试。

A new British startup believes that artificial intelligence is the key to speedrunning the slow and temperamental process of drug design.

Potential Sciences plans to build large-scale chemical datasets by using basic principles of physics to simulate interactions between atoms, then small molecules, then complex amino acids and proteins. With that data, it’s betting it can train AI models and prediction systems capable of identifying highly targeted drugs for specific diseases, bypassing costly and time-consuming lab experimentation.

“We want molecules that are never going to work in the clinic to fail fast,” Hatem Helal, Potential Science’s founder and CEO, tells WIRED. “That means having better predictors of how they will behave as they interact with human biology.”

The startup, which launched on November 5, says it has seed funding in the tens of millions of dollars from SovAI—the UK government’s AI venture capital fund—and Twin Path Ventures, among other investors. The founders declined to disclose the precise figure or valuation.

If things pan out as Potential Sciences hopes, it could pave the way for the accelerated development of new treatments for all sorts of diseases. By reducing the cost of experimentation, Helal says, the company’s approach could also make it economical for pharmaceutical companies to pursue drugs for rare conditions that have previously gone untreated.

#Potential Sciences#SovAI#Twin Path Ventures#Basecamp Research#Isomorphic Labs#CuspAI

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