BioMysteryBench

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1. 2d
   Anthropic builds its own biology lab as Claude flags a novel enzyme system

   Reuters reported, and Anthropic life-sciences lead Eric Kauderer-Abrams confirmed, that the company has set up its own biology lab in the San Francisco Bay Area while continuing to work with outside labs. In an early result, about 950 Claude agents analyzed more than 200,000 reverse transcriptase sequences and flagged a new enzyme system, ART (array-associated reverse transcriptases), whose repeat arrays resemble CRISPR; experiments confirmed short RNA expression but not the system's function. In an earlier protein-design study, Claude did not replace specialist models such as RFdiffusion but organized them and filtered candidates, and 354 of 1,320 designs sent to an external lab bound their targets (about 26.8% hit rate), with successes on 14 of 15 targets.

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